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It seems to me that some of the cast are new to voice acting, which could be either a good or bad thing, if I am not mistaken. To me, it shows that they are putting an effort into finding great voice choices that fit the characters, like Lau, for example. The choice for him was spot-on! His actor is also known as the voice of "Barry the Chopper" from FullMetal Alchemist, and if you've ever seen the dub for that series, you will know what to expect. I also agree with the actress choice for Mei Lin, and for the same reason. Her actress is known for the voices of "Bulma" from Dragon Ball Z, and "Towa" from D.N. Angel among others. If you really know these characters, you would agree that if handled well, these actors could actually portray their personalities we know and love without a hitch (I hope)!
I also believe the fact that Madame Red and William's actors have yet to be announced is another example of choice effort, but this is just my opinion.
UPDATE
It was just brought to my attention that the voice actress for Angelina Durless, also known as "Madame Red," has already been decided, and will be Lydia Mackay, the voice of "Trisha Elric" from Fullmetal Alchemist.
